Research
For over two decades, Bruce and his team have been developing and utilizing computer, AI, and systems approaches, methods, models, and tools to help decision makers better understand and address complex systems in health and public health. This has included the research efforts described below and other initiatives described here.
Bruce has been the Principal Investigator for over $60 million in grants/contracts from a variety of organizations and agencies including the National Institutes of Health (NIH), the Agency for Healthcare Quality and Research (AHRQ), the National Science Foundation (NSF), the Centers for Disease Control and Prevention (CDC), UNICEF, the Global Fund, the Bill & Melinda Gates Foundation, and the U.S. Agency for International Development (USAID).
Bruce and his PHICOR team have published over 295 publications in scientific peer-reviewed journals (e.g., The Lancet, Health Affairs, The New England Journal of Medicine, American Journal of Public Health, American Journal of Preventive Medicine) with Dr. Lee being first author for over 110 and last author for over 120 of them, most of which have been original research. Much of this research has involved working directly with a range of different local, state, national, and international decision-makers.
To find or sort these different scientific publications by topic, use the filtering option below and to the left.
An economic model: value of antimicrobial-coated sutures to society, hospitals, and third-party payers in preventing abdominal surgical site infections
An economic model: value of antimicrobial-coated sutures to society, hospitals, and third-party payers in preventing abdominal surgical site infections
Modeling the economic and epidemiological impact of hookworm vaccine and mass drug administration (MDA) in Brazil, a high transmission setting
Modeling the economic and epidemiological impact of hookworm vaccine and mass drug administration (MDA) in Brazil, a high transmission setting
Global economic burden of norovirus gastroenteritis
Global economic burden of norovirus gastroenteritis
Beyond the Intensive Care Unit (ICU): Countywide impact of universal ICU Staphylococcus aureus decolonization
Beyond the Intensive Care Unit (ICU): Countywide impact of universal ICU Staphylococcus aureus decolonization
The potential trajectory of carbapenem-resistant enterobacteriaceae, an emerging threat to health-care facilities, and the impact of the Centers for Disease Control (CDC) and prevention toolkit
The potential trajectory of carbapenem-resistant enterobacteriaceae, an emerging threat to health-care facilities, and the impact of the Centers for Disease Control (CDC) and prevention toolkit
Cerebral blood flow effects of pain and acupuncture: A preliminary SPECT imaging study
Cerebral blood flow effects of pain and acupuncture: A preliminary SPECT imaging study
A computer simulation of employee vaccination to mitigate an influenza epidemic
A computer simulation of employee vaccination to mitigate an influenza epidemic
Using a computational model to quantify the potential impact of changing the placement of healthy beverages in stores as an intervention to "nudge" adolescent behavior choice
Using a computational model to quantify the potential impact of changing the placement of healthy beverages in stores as an intervention to "nudge" adolescent behavior choice
Broad patterns in domestic vector-borne Trypanosoma cruzi transmission dynamics: synanthropic animals and vector control
Broad patterns in domestic vector-borne Trypanosoma cruzi transmission dynamics: synanthropic animals and vector control
Healthy versus unhealthy suppliers in food desert neighborhoods: A network analysis of corner stores' food supplier networks
Healthy versus unhealthy suppliers in food desert neighborhoods: A network analysis of corner stores' food supplier networks
Weekends as social distancing and their effect on the spread of influenza
Weekends as social distancing and their effect on the spread of influenza
Quantifying the exposure to antibiotic-resistant pathogens among patients discharges from a single hospital across all California healthcare facilities
Quantifying the exposure to antibiotic-resistant pathogens among patients discharges from a single hospital across all California healthcare facilities
An economic model assessing the value of microneedle patch delivery of the seasonal influenza vaccine
An economic model assessing the value of microneedle patch delivery of the seasonal influenza vaccine
Landscaping the structures of GAVI country vaccine supply chains and testing the effects of radical redesign
Landscaping the structures of GAVI country vaccine supply chains and testing the effects of radical redesign
Vital signs: Estimated effects of a coordinated approach for action to reduce antibiotic-resistant infections in Health Care facilities
Vital signs: Estimated effects of a coordinated approach for action to reduce antibiotic-resistant infections in Health Care facilities
One size does not fit all: The impact of primary vaccine container size on vaccine distribution and delivery
One size does not fit all: The impact of primary vaccine container size on vaccine distribution and delivery
Modular vaccine packaging increases packing efficiency
Modular vaccine packaging increases packing efficiency
The Benin experience: How computational modeling can assist major vaccine policy changes in low and middle income countries
The Benin experience: How computational modeling can assist major vaccine policy changes in low and middle income countries
Costs of vaccine programs across 94 low-and middle- income countries
Costs of vaccine programs across 94 low-and middle- income countries
Quantifying the economic value and quality of life impact of earlier influenza vaccination
Quantifying the economic value and quality of life impact of earlier influenza vaccination
Economic impact of norovirus outbreaks in hospitals
Economic impact of norovirus outbreaks in hospitals
Systematic review and cost analysis of pre-operative Chlorhexidine skin antiseptic versus iodine for preventing surgical site infections
Systematic review and cost analysis of pre-operative Chlorhexidine skin antiseptic versus iodine for preventing surgical site infections
Quantifying inter-hospital patient sharing as a mechanism for infectious disease spread
Quantifying inter-hospital patient sharing as a mechanism for infectious disease spread
The economic effect of screening orthopedic surgery patients pre-operatively for methicillin-resistant Staphylococcus aureus
The economic effect of screening orthopedic surgery patients pre-operatively for methicillin-resistant Staphylococcus aureus
Economic impact of Acinetobacter baumannii in the intensive care unit (ICU)
Economic impact of Acinetobacter baumannii in the intensive care unit (ICU)
The potential regional impact of contact precaution use in nursing homes to control methicillin-resistant Staphylococcus aureus (MRSA)
The potential regional impact of contact precaution use in nursing homes to control methicillin-resistant Staphylococcus aureus (MRSA)
Universal methicillin-resistant Staphylococcus aureus (MRSA) surveillance for adult hospital admissions: An economic model and analysis
Universal methicillin-resistant Staphylococcus aureus (MRSA) surveillance for adult hospital admissions: An economic model and analysis
Should vascular surgery patients be screened pre-operatively for methicillin-resistant Staphylococcus aureus (MRSA)
Should vascular surgery patients be screened pre-operatively for methicillin-resistant Staphylococcus aureus (MRSA)
Modeling the spread of methicillin-resistant Staphylococcus aureus (MRSA) outbreaks throughout the hospitals in Orange County, California
Modeling the spread of methicillin-resistant Staphylococcus aureus (MRSA) outbreaks throughout the hospitals in Orange County, California
Economic value of dispensing home-based preoperative chlorhexidine bathing cloths to prevent surgical site infection
Economic value of dispensing home-based preoperative chlorhexidine bathing cloths to prevent surgical site infection
Comparing the economic and health benefits of different approaches to diagnosing Clostridium difficile infection
Comparing the economic and health benefits of different approaches to diagnosing Clostridium difficile infection
Predicting support for non-pharmaceutical interventions during infectious outbreaks: a four region analysis
Predicting support for non-pharmaceutical interventions during infectious outbreaks: a four region analysis
The impact of human immunodeficiency virus (HIV) co-infection on the economic burden of cutaneous leishmaniasis (CL) in Brazil and potential value of new CL drug treatments
The impact of human immunodeficiency virus (HIV) co-infection on the economic burden of cutaneous leishmaniasis (CL) in Brazil and potential value of new CL drug treatments
The benefits of redesigning Benin's vaccine supply chain
The benefits of redesigning Benin's vaccine supply chain
The spread and control of norovirus outbreaks among hospitals in a region: a simulation model
The spread and control of norovirus outbreaks among hospitals in a region: a simulation model
Unless changes are made in Benin, multiple storage and transport bottlenecks may prevent vaccines from reaching the population
Unless changes are made in Benin, multiple storage and transport bottlenecks may prevent vaccines from reaching the population
Increased Tc-99m-MDP accumulation caused by riding bicycle
Increased Tc-99m-MDP accumulation caused by riding bicycle
A computer simulation model of the cost-effectiveness of routine Staphylococcus aureus screening and decolonization among lung and heart-lung transplant recipients
A computer simulation model of the cost-effectiveness of routine Staphylococcus aureus screening and decolonization among lung and heart-lung transplant recipients
Access to urban acute care services in high- vs. middle-income countries: An analysis of seven cities
Access to urban acute care services in high- vs. middle-income countries: An analysis of seven cities
Geotemporal analysis of Neisseria meningitidis clones in the United States
Geotemporal analysis of Neisseria meningitidis clones in the United States
Contagious diseases in the United States from 1888 to the present
Contagious diseases in the United States from 1888 to the present
A passive cold storage device economic model to evaluate selected immunization location scenarios
A passive cold storage device economic model to evaluate selected immunization location scenarios
Geospatial analytics to evaluate point-of-dispensing sites for mass immunizations in Allegheny County
Geospatial analytics to evaluate point-of-dispensing sites for mass immunizations in Allegheny County
Only adding stationary storage to vaccine supply chains may create and worsen transport bottlenecks
Only adding stationary storage to vaccine supply chains may create and worsen transport bottlenecks
Preparedness for pandemics: Does variation among states affect the nation as a whole?
Preparedness for pandemics: Does variation among states affect the nation as a whole?
Modeling the regional spread and control of vancomycin-resistant Enterococci (VRE)
Modeling the regional spread and control of vancomycin-resistant Enterococci (VRE)
Removing the regional level from the Niger vaccine supply chain
Removing the regional level from the Niger vaccine supply chain
The economic burden of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA)
The economic burden of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA)
Is fidaxomicin worth the cost? An economic analysis
Is fidaxomicin worth the cost? An economic analysis