Research
For over two decades, Bruce and his team have been developing and utilizing computer, AI, and systems approaches, methods, models, and tools to help decision makers better understand and address complex systems in health and public health. This has included the research efforts described below and other initiatives described here.
Bruce has been the Principal Investigator for over $60 million in grants/contracts from a variety of organizations and agencies including the National Institutes of Health (NIH), the Agency for Healthcare Quality and Research (AHRQ), the National Science Foundation (NSF), the Centers for Disease Control and Prevention (CDC), UNICEF, the Global Fund, the Bill & Melinda Gates Foundation, and the U.S. Agency for International Development (USAID).
Bruce and his PHICOR team have published over 295 publications in scientific peer-reviewed journals (e.g., The Lancet, Health Affairs, The New England Journal of Medicine, American Journal of Public Health, American Journal of Preventive Medicine) with Dr. Lee being first author for over 110 and last author for over 120 of them, most of which have been original research. Much of this research has involved working directly with a range of different local, state, national, and international decision-makers.
To find or sort these different scientific publications by topic, use the filtering option below and to the left.
Modeling Health and Economic Outcomes of Eliminating Sex Disparities in Youth Physical Activity
Modeling Health and Economic Outcomes of Eliminating Sex Disparities in Youth Physical Activity
JAMA Network Open
Response to: “Quantifying the effect of vaccination on transmission in modelling studies”
Response to: “Quantifying the effect of vaccination on transmission in modelling studies”
The Lancet
What is the economic benefit of annual COVID-19 vaccination from the adult individual perspective?
What is the economic benefit of annual COVID-19 vaccination from the adult individual perspective?
The Journal of Infectious Disease
Health and Economic Value of Eliminating Socioeconomic Disparities in US Youth Physical Activity.
Health and Economic Value of Eliminating Socioeconomic Disparities in US Youth Physical Activity.
JAMA Network
How the Timing of Annual COVID-19 Vaccination of Nursing Home Residents and Staff Affects its Value.
How the Timing of Annual COVID-19 Vaccination of Nursing Home Residents and Staff Affects its Value.
The Journal of the Post-Acute and Long-Term Care Medical Association
Qualitative systems mapping in promoting physical activity and cardiorespiratory fitness: Perspectives and recommendations.
Qualitative systems mapping in promoting physical activity and cardiorespiratory fitness: Perspectives and recommendations.
Progress in Cardiovascular Diseases
Benefits of Meeting the Healthy People 2030 Youth Sports Participation Target.
Benefits of Meeting the Healthy People 2030 Youth Sports Participation Target.
American Journal of Preventive Medicine
Cost-Effectiveness of SARS-CoV-2 Testing and Isolation Strategies in Nursing Homes.
Cost-Effectiveness of SARS-CoV-2 Testing and Isolation Strategies in Nursing Homes.
Infection Control & Hospital Epidemiology
The potential epidemiologic, clinical, and economic value of a universal coronavirus vaccine: a modelling study.
The potential epidemiologic, clinical, and economic value of a universal coronavirus vaccine: a modelling study
The Lancet
The Need for Systems Approaches for Precision Communications in Public Health.
The Need for Systems Approaches for Precision Communications in Public Health.
The Journal of Health Communication
Food insecurity is under-reported in surveys that ask about the past year.
Food insecurity is under-reported in surveys that ask about the past year.
American Journal of Preventive Medicine
When increasing vegetable production may worsen food availability gaps: A simulation model in India
When increasing vegetable production may worsen food availability gaps: A simulation model in India
Food Policy
Research gaps and opportunities in precision nutrition: an NIH workshop report
Research gaps and opportunities in precision nutrition: an NIH workshop report
American Journal of Clinical Nutrition
The value of decreasing the duration of the infectious period of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection
The value of decreasing the duration of the infectious period of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection
PLos Computational Biology
The benefits of vaccinating with the first available COVID-19 coronavirus vaccine
The benefits of vaccinating with the first available COVID-19 coronavirus vaccine
American Journal of Preventive Medicine
The impact of a place-tailored digital health app promoting exercise classes on african american women’s physical activity and obesity: Simulation study
The impact of a place-tailored digital health app promoting exercise classes on african american women’s physical activity and obesity: Simulation study
Journal of Medical Internet Research
Lives and Costs Saved by Expanding and Expediting Coronavirus Disease 2019 Vaccination
Lives and costs saved by expanding and expediting coronavirus disease 2019 vaccination
Journal of Infectious Disease
Overcoming misconceptions and integrating systems approached into cancer research
Overcoming misconceptions and integrating systems approached into cancer research
PLOS Medicine
The potential epidemiologic, clinical, and economic impact of requiring schools to offer Physical Education (PE) classes in Mexico City
The potential epidemiologic, clinical, and economic impact of requiring schools to offer Physical Education (PE) classes in Mexico City
PLOS One
The impact of reducing the frequency of night feeding on infant BMI
The impact of reducing the frequency of night feeding on infant BMI
Pediatric Research
A systems map of the economic considerations for vaccination: Application to hard-to-reach populations
A systems map of the economic considerations for vaccination: Application to hard-to-reach populations
Vaccine
Maintaining face mask use before and after achieving different COVID-19 vaccination coverage levels: a modelling study
Maintaining face mask use before and after achieving different COVID-19 vaccination coverage levels: a modelling study
Lancet Public Health
The potential clinical and economic value of a human papillomavirus primary screening test that additionally identifies genotypes 31, 45, 51, and 52 individually
The potential clinical and economic value of a human papillomavirus primary screening test that additionally identifies genotypes 31, 45, 51, and 52 individually
Sexually Transmitted Diseases
How long-term acute care hospitals (LTACHs) can play an important role in controlling carbapenem-resistant enterobacteriaceae (CRE) in a region: A simulation modeling study
How long-term acute care hospitals (LTACHs) can play an important role in controlling carbapenem-resistant enterobacteriaceae (CRE) in a region: A simulation modeling study
American Journal of Epidemiology
How to choose target facilities in a region to implement carbapenem-resistant Enterobacteriaceae (CRE) control measures
How to choose target facilities in a region to implement carbapenem-resistant Enterobacteriaceae (CRE) control measures
Clinical Infectious Disease
Potential clinical and economic value of norovirus vaccination in the community setting
Potential clinical and economic value of norovirus vaccination in the community setting
American Journal of Preventive Medicine
Estimated number of N95 respirators needed for healthcare workers in acute-care hospitals during the coronavirus disease 2019 (COVID-19) pandemic
Estimated number of N95 respirators needed for healthcare workers in acute-care hospitals during the coronavirus disease 2019 (COVID-19) pandemic
Infection Control and Hospital Epidemiology
Big data and systems methods: The next frontier to tackling the global obesity epidemic
Big data and systems methods: The next frontier to tackling the global obesity epidemic
Obesity
The clinical and economic burden of norovirus gastroenteritis in the United States
The clinical and economic burden of norovirus gastroenteritis in the United States
Journal of Infectious Disease
Replacing the measles multi-dose vaccine presentation with the single-dose presentation in Thailand
Replacing the measles multi-dose vaccine presentation with the single-dose presentation in Thailand
Vaccine
Economic value of Acinetobacter baumannii screening in the intensive care unit (ICU)
Economic value of Acinetobacter baumannii screening in the intensive care unit (ICU)
Clinical Microbiology Infection
Economic value of dengue vaccine in Thailand
Economic value of dengue vaccine in Thailand
The American Journal of Tropical Medicine and Hygiene
What if the influenza vaccine did not offer such variable protection?
What if the influenza vaccine did not offer such variable protection?
Vaccine efficacy needed for a COVID-19 coronavirus vaccine to prevent or stop an epidemic as the sole intervention
Vaccine efficacy needed for a COVID-19 coronavirus vaccine to prevent or stop an epidemic as the sole intervention
AJPM’s Paper of the Year 2020
Childhood obesity evidence base project: Methods for taxonomy development for application in taxonomic meta-analysis.
Childhood obesity evidence base project: Methods for taxonomy development for application in taxonomic meta-analysis.
Childhood Obesity
Childhood obesity evidence base project: A systematic review and meta-analysis of a new taxonomy of intervention components to improve weight status in children 2-5 years of age, 2005-2019
Childhood obesity evidence base project: A systematic review and meta-analysis of a new taxonomy of intervention components to improve weight status in children 2-5 years of age, 2005-2019
Childhood Obesity
Knowing more of the iceberg: How detecting a greater proportion of carbapenem-resistant Enterobacteriaceae (CRE) carriers impacts transmission
Knowing more of the iceberg: How detecting a greater proportion of carbapenem-resistant Enterobacteriaceae (CRE) carriers impacts transmission
The Journal of Infectious Diseases
The benefits to all of ensuring equal and timely access to influenza vaccines in poor communities
The benefits to all of ensuring equal and timely access to influenza vaccines in poor communities
Health Affairs
Would school closure for the 2009 H1N1 influenza epidemic have been worth the cost
Would school closure for the 2009 H1N1 influenza epidemic have been worth the cost
BMC Public Health
Using simulation modeling to guide the design of the girl scouts fierce & fit program
Using simulation modeling to guide the design of the girl scouts fierce & fit program
Obesity
The potential healthcare cost and resource use associated with COVID-19 coronavirus in the United States
The potential healthcare cost and resource use associated with COVID-19 coronavirus in the United States
Health Affairs
The potential economic value of a therapeutic chagas disease vaccine for pregnant women to prevent congenital transmission
The potential economic value of a therapeutic chagas disease vaccine for pregnant women to prevent congenital transmission
Vaccine
Can following formula-feeding recommendations still result in infants who are overweight or have obesity?
Can following formula-feeding recommendations still result in infants who are overweight or have obesity?
Pediatric Research
Vaccine eligibility and acceptance among ambulatory obstetric and gynecologic patients
Vaccine eligibility and acceptance among ambulatory obstetric and gynecologic patients
Vaccine
How introducing a registry with automated alerts for carbapenem-resistant Enterobacteriaceae (CRE) may help control CRE spread in a region
How introducing a registry with automated alerts for carbapenem-resistant Enterobacteriaceae (CRE) may help control CRE spread in a region
Clinical Infectious Diseases
The potential economic value of a Zika vaccine for a woman of childbearing age
The potential economic value of a Zika vaccine for a woman of childbearing age
American Journal of Preventive Medicine
The economic value of screening hemodialysis patients for methicillin-resistant Staphylococcus aureus (MRSA) in the United States
The economic value of screening hemodialysis patients for methicillin-resistant Staphylococcus aureus (MRSA) in the United States
Clinical Microbiology and Infection
The impact of following solid food feeding guides on BMI among infants: A simulation study
The impact of following solid food feeding guides on BMI among infants: A simulation study
American Journal of Preventive Medicine
How coping can hide larger systems problems: The routine immunization supply chain in Bihar, India
How coping can hide larger systems problems: The routine immunization supply chain in Bihar, India
BMJ Global Health
The role of subway travel in an influenza epidemic: a New York City simulation
The role of subway travel in an influenza epidemic: a New York City simulation
Journal of Urban Health