Research
For over two decades, Bruce and his team have been developing and utilizing computer, AI, and systems approaches, methods, models, and tools to help decision makers better understand and address complex systems in health and public health. This has included the research efforts described below and other initiatives described here.
Bruce has been the Principal Investigator for over $60 million in grants/contracts from a variety of organizations and agencies including the National Institutes of Health (NIH), the Agency for Healthcare Quality and Research (AHRQ), the National Science Foundation (NSF), the Centers for Disease Control and Prevention (CDC), UNICEF, the Global Fund, the Bill & Melinda Gates Foundation, and the U.S. Agency for International Development (USAID).
Bruce and his PHICOR team have published over 295 publications in scientific peer-reviewed journals (e.g., The Lancet, Health Affairs, The New England Journal of Medicine, American Journal of Public Health, American Journal of Preventive Medicine) with Dr. Lee being first author for over 110 and last author for over 120 of them, most of which have been original research. Much of this research has involved working directly with a range of different local, state, national, and international decision-makers.
To find or sort these different scientific publications by topic, use the filtering option below and to the left.
Modeling Health and Economic Outcomes of Eliminating Sex Disparities in Youth Physical Activity
Modeling Health and Economic Outcomes of Eliminating Sex Disparities in Youth Physical Activity
Response to: “Quantifying the effect of vaccination on transmission in modelling studies”
Response to: “Quantifying the effect of vaccination on transmission in modelling studies”
What is the economic benefit of annual COVID-19 vaccination from the adult individual perspective?
What is the economic benefit of annual COVID-19 vaccination from the adult individual perspective?
Cost-Effectiveness of SARS-CoV-2 Testing and Isolation Strategies in Nursing Homes.
Cost-Effectiveness of SARS-CoV-2 Testing and Isolation Strategies in Nursing Homes.
The Need for Systems Approaches for Precision Communications in Public Health.
The Need for Systems Approaches for Precision Communications in Public Health.
A systems map of the economic considerations for vaccination: Application to hard-to-reach populations
A systems map of the economic considerations for vaccination: Application to hard-to-reach populations
How long-term acute care hospitals (LTACHs) can play an important role in controlling carbapenem-resistant enterobacteriaceae (CRE) in a region: A simulation modeling study
How long-term acute care hospitals (LTACHs) can play an important role in controlling carbapenem-resistant enterobacteriaceae (CRE) in a region: A simulation modeling study
How to choose target facilities in a region to implement carbapenem-resistant Enterobacteriaceae (CRE) control measures
How to choose target facilities in a region to implement carbapenem-resistant Enterobacteriaceae (CRE) control measures
Estimated number of N95 respirators needed for healthcare workers in acute-care hospitals during the coronavirus disease 2019 (COVID-19) pandemic
Estimated number of N95 respirators needed for healthcare workers in acute-care hospitals during the coronavirus disease 2019 (COVID-19) pandemic
Replacing the measles multi-dose vaccine presentation with the single-dose presentation in Thailand
Replacing the measles multi-dose vaccine presentation with the single-dose presentation in Thailand
Economic value of Acinetobacter baumannii screening in the intensive care unit (ICU)
Economic value of Acinetobacter baumannii screening in the intensive care unit (ICU)
Knowing more of the iceberg: How detecting a greater proportion of carbapenem-resistant Enterobacteriaceae (CRE) carriers impacts transmission
Knowing more of the iceberg: How detecting a greater proportion of carbapenem-resistant Enterobacteriaceae (CRE) carriers impacts transmission
The potential economic value of a therapeutic chagas disease vaccine for pregnant women to prevent congenital transmission
The potential economic value of a therapeutic chagas disease vaccine for pregnant women to prevent congenital transmission
Vaccine eligibility and acceptance among ambulatory obstetric and gynecologic patients
Vaccine eligibility and acceptance among ambulatory obstetric and gynecologic patients
How introducing a registry with automated alerts for carbapenem-resistant Enterobacteriaceae (CRE) may help control CRE spread in a region
How introducing a registry with automated alerts for carbapenem-resistant Enterobacteriaceae (CRE) may help control CRE spread in a region
The economic value of screening hemodialysis patients for methicillin-resistant Staphylococcus aureus (MRSA) in the United States
The economic value of screening hemodialysis patients for methicillin-resistant Staphylococcus aureus (MRSA) in the United States
How coping can hide larger systems problems: The routine immunization supply chain in Bihar, India
How coping can hide larger systems problems: The routine immunization supply chain in Bihar, India
Epidemiologic and economic impact of methicillin-resistant Staphylococcus aureus in obstetrics
Epidemiologic and economic impact of methicillin-resistant Staphylococcus aureus in obstetrics
Economic value of vaccinating geographically hard-to-reach populations with measles vaccine: Modeling application in Kenya
Economic value of vaccinating geographically hard-to-reach populations with measles vaccine: Modeling application in Kenya
The SHIELD Orange County project -multi drug- resistant organism (MDRO) prevalence in 21 nursing homes and long term acute care facilities in southern California
The SHIELD Orange County project -multi drug- resistant organism (MDRO) prevalence in 21 nursing homes and long term acute care facilities in southern California
The value of tailoring vial sizes to populations and locations
The value of tailoring vial sizes to populations and locations
The potential effects of introducing microneedle patch vaccines into routine vaccine supply chain
The potential effects of introducing microneedle patch vaccines into routine vaccine supply chain
Dual-chamber injection device for measles-rubella vaccine: The potential impact of introducing varying sizes of the devices in 3 countries
Dual-chamber injection device for measles-rubella vaccine: The potential impact of introducing varying sizes of the devices in 3 countries
The economic value of the Centers for Disease Control and Prevention (CDC) Carbapenem-Resistant Enterobacteriaceae (CRE) toolkit
The economic value of the Centers for Disease Control and Prevention (CDC) Carbapenem-Resistant Enterobacteriaceae (CRE) toolkit
The importance of vaccine supply chains to everyone in the vaccine world
The importance of vaccine supply chains to everyone in the vaccine world
The economic value of long-lasting insecticidal Nets (LLINs) and indoor residual spraying (IRS) implementation in Mozambique
The economic value of long-lasting insecticidal Nets (LLINs) and indoor residual spraying (IRS) implementation in Mozambique
System redesign of the immunization supply chain: experiences from Benin and Mozambique
System redesign of the immunization supply chain: experiences from Benin and Mozambique
When are solar refrigerators less costly than on-grid refrigerators: A simulation modeling study
When are solar refrigerators less costly than on-grid refrigerators: A simulation modeling study
A systems approach to vaccine decision making
A systems approach to vaccine decision making
Map of different vaccine supply chain efficiency measures
Map of different vaccine supply chain efficiency measures
Impact of delays between the Clinical and Laboratory Standards Institute (CLSI) and the Food and Drug Administration (FDA)
Impact of delays between the Clinical and Laboratory Standards Institute (CLSI) and the Food and Drug Administration (FDA) revising interpretive criteria for Carbapenem-Resistant Enterobacteriaceae (CRE)
Re-designing the Mozambique vaccine supply chain to improve access to vaccines
Re-designing the Mozambique vaccine supply chain to improve access to vaccines
The economic value of increasing geospatial access to tetanus toxoid immunization in Mozambique
The economic value of increasing geospatial access to tetanus toxoid immunization in Mozambique
The economic and operational value of using drones to transport vaccines
The economic and operational value of using drones to transport vaccines
The impact of implementing a demand forecasting system into a low-income country’s supply chain
The impact of implementing a demand forecasting system into a low-income country’s supply chain
An economic model: value of antimicrobial-coated sutures to society, hospitals, and third-party payers in preventing abdominal surgical site infections
An economic model: value of antimicrobial-coated sutures to society, hospitals, and third-party payers in preventing abdominal surgical site infections
Modeling the economic and epidemiological impact of hookworm vaccine and mass drug administration (MDA) in Brazil, a high transmission setting
Modeling the economic and epidemiological impact of hookworm vaccine and mass drug administration (MDA) in Brazil, a high transmission setting
Beyond the Intensive Care Unit (ICU): Countywide impact of universal ICU Staphylococcus aureus decolonization
Beyond the Intensive Care Unit (ICU): Countywide impact of universal ICU Staphylococcus aureus decolonization
The potential trajectory of carbapenem-resistant enterobacteriaceae, an emerging threat to health-care facilities, and the impact of the Centers for Disease Control (CDC) and prevention toolkit
The potential trajectory of carbapenem-resistant enterobacteriaceae, an emerging threat to health-care facilities, and the impact of the Centers for Disease Control (CDC) and prevention toolkit
Landscaping the structures of GAVI country vaccine supply chains and testing the effects of radical redesign
Landscaping the structures of GAVI country vaccine supply chains and testing the effects of radical redesign
Vital signs: Estimated effects of a coordinated approach for action to reduce antibiotic-resistant infections in Health Care facilities
Vital signs: Estimated effects of a coordinated approach for action to reduce antibiotic-resistant infections in Health Care facilities
One size does not fit all: The impact of primary vaccine container size on vaccine distribution and delivery
One size does not fit all: The impact of primary vaccine container size on vaccine distribution and delivery
Modular vaccine packaging increases packing efficiency
Modular vaccine packaging increases packing efficiency
The Benin experience: How computational modeling can assist major vaccine policy changes in low and middle income countries
The Benin experience: How computational modeling can assist major vaccine policy changes in low and middle income countries
Costs of vaccine programs across 94 low-and middle- income countries
Costs of vaccine programs across 94 low-and middle- income countries
Quantifying the economic value and quality of life impact of earlier influenza vaccination
Quantifying the economic value and quality of life impact of earlier influenza vaccination
Economic impact of norovirus outbreaks in hospitals
Economic impact of norovirus outbreaks in hospitals
Systematic review and cost analysis of pre-operative Chlorhexidine skin antiseptic versus iodine for preventing surgical site infections
Systematic review and cost analysis of pre-operative Chlorhexidine skin antiseptic versus iodine for preventing surgical site infections
Quantifying inter-hospital patient sharing as a mechanism for infectious disease spread
Quantifying inter-hospital patient sharing as a mechanism for infectious disease spread